Anti Calcium/calmodulin-dependent protein kinase II, Isoform C (dCAMKII) mAb (Clone 18)

Cosmo Bio

Catalog No: CAC-TNL-001-CAM

Ca2+/calmodulin-dependent protein kinase II (CaM kinase II or CaMKII) is a serine/threonine-specific protein kinase that is regulated by the Ca2+/calmodulin complex. CaMKII is involved in many signaling cascades and is thought to be an important mediator of learning and memory.[1] CaMKII is also necessary for Ca2+ homeostasis and reuptake in cardiomyocytes,[2] chloride transport in epithelia,[3] positive T-cell selection,[4] and CD8 T-cell activation.[5] Misregulation of CaMKII is linked to Alzheimer’s disease, Angelman syndrome, and heart arrhythmia.[6] [from: Wikipedia contributors. (2019, March 15). Ca2+/calmodulin-dependent protein kinase II. In Wikipedia, The Free Encyclopedia. Retrieved 20:14, June 4, 2019, from https://en.wikipedia.org/w/index.php?title=Ca2%2B/calmodulin-dependent_protein_kinase_II&oldid=887834881]

References:
Takamatsu Y, Kishimoto Y and Ohsako S. (2003) Immunohistochemical study of Ca2+/calmodulin-dependent protein kinase II in the Drosophila brain using a specific monoclonal antibody. Brain Res. 974:99-116.

 

Product Specifications

• Application: IHC(f), WB, IHC(p), IF
• Reactivity: Drosophila
• Clonality: Monoclonal (Clone No.: 18)
• Host: Mouse

Citations for Anti Calcium/calmodulin-dependent protein kinase II, Isoform C (dCAMKII) mAb (Clone 18) – 2 Found

Schwartz, Silvia; Truglio, Mauro; Scott, Maxwell J; Fitzsimons, Helen L. Long-Term Memory in Drosophila Is Influenced by Histone Deacetylase HDAC4 Interacting with SUMO-Conjugating Enzyme Ubc9. Genetics. 2016;203(3):1249-64. 

Liu, Pengcheng; Peng, Hong-Juan; Zhu, Jinsong. Juvenile hormone-activated phospholipase C pathway enhances transcriptional activation by the methoprene-tolerant protein. Proceedings Of The National Academy Of Sciences Of The United States Of America. 2015;112(15):E1871-9.