Application: IHC, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide (PubMed:11159812). Catalyzes 4-beta-hydroxylation of cholesterol. May catalyze 25-hydroxylation of cholesterol in vitro (PubMed:21576599).
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide (PubMed:11159812). Catalyzes 4-beta-hydroxylation of cholesterol. May catalyze 25-hydroxylation of cholesterol in vitro (PubMed:21576599).
Documents & Links for Anti CYP3A4 mAb (Clone 10B10) | |
Datasheet | Anti CYP3A4 mAb (Clone 10B10) Datasheet |
Vendor Page | Anti CYP3A4 mAb (Clone 10B10) at CUSABIO |
Documents & Links for Anti CYP3A4 mAb (Clone 10B10) | |
Datasheet | Anti CYP3A4 mAb (Clone 10B10) Datasheet |
Vendor Page | Anti CYP3A4 mAb (Clone 10B10) |