Application: IF, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.
| Documents & Links for Anti CXCR4 mAb (Clone 2F10) | |
| Datasheet | Anti CXCR4 mAb (Clone 2F10) Datasheet |
| Vendor Page | Anti CXCR4 mAb (Clone 2F10) at CUSABIO |
| Documents & Links for Anti CXCR4 mAb (Clone 2F10) | |
| Datasheet | Anti CXCR4 mAb (Clone 2F10) Datasheet |
| Vendor Page | Anti CXCR4 mAb (Clone 2F10) |
