Application: WB, ICC, IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: cyclin-dependent kinase 6
Gene Name: CDK6
Alternative Gene Name: PLSTIRE
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000040274: 92%, ENSRNOG00000009258: 92%
Entrez Gene ID: 1021
Uniprot ID: Q00534
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: cyclin-dependent kinase 6
Gene Name: CDK6
Alternative Gene Name: PLSTIRE
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000040274: 92%, ENSRNOG00000009258: 92%
Entrez Gene ID: 1021
Uniprot ID: Q00534
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Cognate Antibody/Antigen for Anti CDK6 pAb (ATL-HPA002637 w/enhanced validation) | |
Antigen | PrEST Antigen CDK6 (ATL-APrEST86426) |
Documents & Links for Anti CDK6 pAb (ATL-HPA002637 w/enhanced validation) | |
Datasheet | Anti CDK6 pAb (ATL-HPA002637 w/enhanced validation) Datasheet (External Link) |
Vendor Page | Anti CDK6 pAb (ATL-HPA002637 w/enhanced validation) at Atlas |
Documents & Links for Anti CDK6 pAb (ATL-HPA002637 w/enhanced validation) | |
Datasheet | Anti CDK6 pAb (ATL-HPA002637 w/enhanced validation) Datasheet (External Link) |
Vendor Page | Anti CDK6 pAb (ATL-HPA002637 w/enhanced validation) |
Citations for Anti CDK6 pAb (ATL-HPA002637 w/enhanced validation) – 4 Found |
Loss of the FAT1 Tumor Suppressor Promotes Resistance to CDK4/6 Inhibitors via the Hippo Pathway. Cancer Cell. 2018 Dec 10;34(6):893-905.e8. doi: 10.1016/j.ccell.2018.11.006. PubMed |
The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis. J Clin Invest. 2020 Nov 2;130(11):5765-5781. doi: 10.1172/JCI134217. PubMed |
Requirement of DNMT1 to orchestrate epigenomic reprogramming for NPM-ALK-driven lymphomagenesis. Life Sci Alliance. 2020 Dec 11;4(2):e202000794. doi: 10.26508/lsa.202000794. Print 2021 Feb. PubMed |
INK4 Tumor Suppressor Proteins Mediate Resistance to CDK4/6 Kinase Inhibitors. Cancer Discov. 2022 Feb;12(2):356-371. doi: 10.1158/2159-8290.CD-20-1726. Epub 2021 Sep 20. PubMed |