Application: WB, IHC, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human, Mouse
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration. Required for DOCK10-mediated spine formation in Purkinje cells and hippocampal neurons. Facilitates filopodia formation upon DOCK11-activation (By similarity).
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human, Mouse
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration. Required for DOCK10-mediated spine formation in Purkinje cells and hippocampal neurons. Facilitates filopodia formation upon DOCK11-activation (By similarity).
| Documents & Links for Anti CDC42 mAb (Clone 3C3) | |
| Datasheet | Anti CDC42 mAb (Clone 3C3) Datasheet |
| Vendor Page | Anti CDC42 mAb (Clone 3C3) at CUSABIO |
| Documents & Links for Anti CDC42 mAb (Clone 3C3) | |
| Datasheet | Anti CDC42 mAb (Clone 3C3) Datasheet |
| Vendor Page | Anti CDC42 mAb (Clone 3C3) |
