Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
Product Specifications |
Application |
IHC, FC, ELISA |
Reactivity |
Human |
Clonality |
Monoclonal (Clone No.: 8H11) |