Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.
| Product Specifications | |
| Application | WB, IHC, ELISA |
| Reactivity | Human |
| Clonality | Monoclonal (Clone No.: 7D12) |
| Documents & Links for Anti CD46 mAb (Clone 7D12) | |
| Datasheet | Anti CD46 mAb (Clone 7D12) Datasheet |
| Vendor Page | Anti CD46 mAb (Clone 7D12) at CUSABIO |
| Documents & Links for Anti CD46 mAb (Clone 7D12) | |
| Datasheet | Anti CD46 mAb (Clone 7D12) Datasheet |
| Vendor Page | Anti CD46 mAb (Clone 7D12) |