Anti-CD274 (PD-L1) (Human) mAb (Clone: 27A2)

Catalog No:
MBL-D230-3

Availability: 12PM PT on Dec. 3, 2024

Monoclonal antibody of 100 μg targeting CD274 for FCM, IHC.



Product Specifications
Application FC, IHC
Reactivity Human
Clonality Monoclonal IgG2b
Host Mouse
Immunogen Recombinant human PD-L1 extracellular domain
Gene ID - Human

29126

Gene ID - Mouse

60533

Formulation 100 μg IgG in 100 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative iscontained.

Citations for Anti-CD274 (PD-L1) (Human) mAb (Clone: 27A2) – 9 Found
Bridges-Webb, C. General practitioners and over-servicing. The Medical Journal Of Australia. 1992;156(2):140-1.  PubMed
Comments: Used in: IHC
Schuchmann, M; Meyer, R G; Distler, E; von Stebut, E; Kuball, J; Schnürer, E; Wölfel, T; Theobald, M; Konur, A; Gregor, S; Schreiner, O; Huber, C; Galle, P R; Otto, G; Herr, W. The programmed death (PD)-1/PD-ligand 1 pathway regulates graft-versus-host-reactive CD8 T cells after liver transplantation. American Journal Of Transplantation : Official Journal Of The American Society Of Transplantation And The American Society Of Transplant Surgeons. 2008;8(11):2434-44.  PubMed
Comments: Used in: IHC
Hino, Ryosuke; Kabashima, Kenji; Kato, Yu; Yagi, Hiroaki; Nakamura, Motonobu; Honjo, Tasuku; Okazaki, Taku; Tokura, Yoshiki. Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma. Cancer. 2010;116(7):1757-66.  PubMed
Comments: Used in: IHC
Gadiot, Jules; Hooijkaas, Anna I; Kaiser, Andrew D M; van Tinteren, Harm; van Boven, Hester; Blank, Christian. Overall survival and PD-L1 expression in metastasized malignant melanoma. Cancer. 2011;117(10):2192-201.  PubMed
Comments: Used in: IHC
Droeser, Raoul A; Hirt, Christian; Viehl, Carsten T; Frey, Daniel M; Nebiker, Christian; Huber, Xaver; Zlobec, Inti; Eppenberger-Castori, Serenella; Tzankov, Alexander; Rosso, Raffaele; Zuber, Markus; Muraro, Manuele Giuseppe; Amicarella, Francesca; Cremonesi, Eleonora; Heberer, Michael; Iezzi, Giandomenica; Lugli, Alessandro; Terracciano, Luigi; Sconocchia, Giuseppe; Oertli, Daniel; Spagnoli, Giulio C; Tornillo, Luigi. Clinical impact of programmed cell death ligand 1 expression in colorectal cancer. European Journal Of Cancer (Oxford, England : 1990). 2013;49(9):2233-42.  PubMed
Comments: Used in: IHC
Hamanishi, Junzo; Mandai, Masaki; Ikeda, Takafumi; Minami, Manabu; Kawaguchi, Atsushi; Murayama, Toshinori; Kanai, Masashi; Mori, Yukiko; Matsumoto, Shigemi; Chikuma, Shunsuke; Matsumura, Noriomi; Abiko, Kaoru; Baba, Tsukasa; Yamaguchi, Ken; Ueda, Akihiko; Hosoe, Yuko; Morita, Satoshi; Yokode, Masayuki; Shimizu, Akira; Honjo, Tasuku; Konishi, Ikuo. Safety and Antitumor Activity of Anti-PD-1 Antibody, Nivolumab, in Patients With Platinum-Resistant Ovarian Cancer. Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology. 2015;33(34):4015-22.  PubMed
Comments: Used in: IHC
Wu, X; Zhang, H; Xing, Q; Cui, J; Li, J; Li, Y; Tan, Y; Wang, S. PD-1(+) CD8(+) T cells are exhausted in tumours and functional in draining lymph nodes of colorectal cancer patients. British Journal Of Cancer. 2014;111(7):1391-9.  PubMed
Comments: Used in: IHC
Goto, Wataru; Kashiwagi, Shinichiro; Asano, Yuka; Takada, Koji; Morisaki, Tamami; Fujita, Hisakazu; Takashima, Tsutomu; Ohsawa, Masahiko; Hirakawa, Kosei; Ohira, Masaichi. Eribulin Promotes Antitumor Immune Responses in Patients with Locally Advanced or Metastatic Breast Cancer. Anticancer Research. 2018;38(5):2929-2938.  PubMed
Comments: Used in: IHC
Ito, Nozomi; Tsujimoto, Hironori; Horiguchi, Hiroyuki; Shimazaki, Hideyuki; Miyazaki, Hiromi; Saitoh, Daizoh; Kishi, Yoji; Ueno, Hideki. Clinical Significance of Programmed Death Ligand-1 Expression in Esophageal Squamous Cell Carcinoma. The Journal Of Surgical Research. 2020;251:321-328.  PubMed
Comments: Used in: IHC