Application: WB, IHC, IF, FC, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
| Documents & Links for Anti CD146 mAb (Clone 8A10) | |
| Datasheet | Anti CD146 mAb (Clone 8A10) Datasheet |
| Vendor Page | Anti CD146 mAb (Clone 8A10) at CUSABIO |
| Documents & Links for Anti CD146 mAb (Clone 8A10) | |
| Datasheet | Anti CD146 mAb (Clone 8A10) Datasheet |
| Vendor Page | Anti CD146 mAb (Clone 8A10) |
