May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Product Specifications | |
Application | IHC, ELISA |
Reactivity | Human |
Clonality | Monoclonal (Clone No.: 3A12) |
Documents & Links for Anti CCL19 mAb (Clone 3A12) | |
Datasheet | Anti CCL19 mAb (Clone 3A12) Datasheet |
Vendor Page | Anti CCL19 mAb (Clone 3A12) at CUSABIO |
Documents & Links for Anti CCL19 mAb (Clone 3A12) | |
Datasheet | Anti CCL19 mAb (Clone 3A12) Datasheet |
Vendor Page | Anti CCL19 mAb (Clone 3A12) |