Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
| Product Specifications | |
| Application | WB, IF, FC, ELISA |
| Reactivity | Human |
| Clonality | Monoclonal (Clone No.: 2D5) |
| Documents & Links for Anti CASP9 mAb (Clone 2D5) | |
| Datasheet | Anti CASP9 mAb (Clone 2D5) Datasheet |
| Vendor Page | Anti CASP9 mAb (Clone 2D5) at CUSABIO |
| Documents & Links for Anti CASP9 mAb (Clone 2D5) | |
| Datasheet | Anti CASP9 mAb (Clone 2D5) Datasheet |
| Vendor Page | Anti CASP9 mAb (Clone 2D5) |