Application: WB, IHC, IF, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
| Documents & Links for Anti CASP3 mAb (Clone 5B2) | |
| Datasheet | Anti CASP3 mAb (Clone 5B2) Datasheet |
| Vendor Page | Anti CASP3 mAb (Clone 5B2) at CUSABIO |
| Documents & Links for Anti CASP3 mAb (Clone 5B2) | |
| Datasheet | Anti CASP3 mAb (Clone 5B2) Datasheet |
| Vendor Page | Anti CASP3 mAb (Clone 5B2) |
