Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
| Product Specifications | |
| Application | WB, IHC, ELISA |
| Reactivity | Human |
| Clonality | Monoclonal (Clone No.: 1F2) |
| Documents & Links for Anti BMI1 mAb (Clone 1F2) | |
| Datasheet | Anti BMI1 mAb (Clone 1F2) Datasheet |
| Vendor Page | Anti BMI1 mAb (Clone 1F2) at CUSABIO |
| Documents & Links for Anti BMI1 mAb (Clone 1F2) | |
| Datasheet | Anti BMI1 mAb (Clone 1F2) Datasheet |
| Vendor Page | Anti BMI1 mAb (Clone 1F2) |