Monoclonal Antibody of 100 μg targeting Atg16L for WB.
| Product Specifications | |
| Application | WB |
| Reactivity | Human, Mouse, Rat |
| Clonality | Monoclonal IgG1 ĸ |
| Host | Mouse |
| Immunogen | Recombinant human ATG16L1 TV2 (85-588 a.a.) |
| Formulation | 100 μg IgG in 100 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained. |
| Citations for Anti-Atg16L mAb (Clone: 1F12) – 14 Found |
| Adolph, Timon E; Tomczak, Michal F; Niederreiter, Lukas; Ko, Hyun-Jeong; Böck, Janne; Martinez-Naves, Eduardo; Glickman, Jonathan N; Tschurtschenthaler, Markus; Hartwig, John; Hosomi, Shuhei; Flak, Magdalena B; Cusick, Jennifer L; Kohno, Kenji; Iwawaki, Takao; Billmann-Born, Susanne; Raine, Tim; Bharti, Richa; Lucius, Ralph; Kweon, Mi-Na; Marciniak, Stefan J; Choi, Augustine; Hagen, Susan J; Schreiber, Stefan; Rosenstiel, Philip; Kaser, Arthur; Blumberg, Richard S. Paneth cells as a site of origin for intestinal inflammation. Nature. 2013;503(7475):272-6. PubMed - Comments: Used in: WB |
| Adolph, Timon E; Tomczak, Michal F; Niederreiter, Lukas; Ko, Hyun-Jeong; Böck, Janne; Martinez-Naves, Eduardo; Glickman, Jonathan N; Tschurtschenthaler, Markus; Hartwig, John; Hosomi, Shuhei; Flak, Magdalena B; Cusick, Jennifer L; Kohno, Kenji; Iwawaki, Takao; Billmann-Born, Susanne; Raine, Tim; Bharti, Richa; Lucius, Ralph; Kweon, Mi-Na; Marciniak, Stefan J; Choi, Augustine; Hagen, Susan J; Schreiber, Stefan; Rosenstiel, Philip; Kaser, Arthur; Blumberg, Richard S. Paneth cells as a site of origin for intestinal inflammation. Nature. 2013;503(7475):272-6. PubMed - Comments: Used in: IHC |
| Myeku, Natura; Figueiredo-Pereira, Maria E. Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62. The Journal Of Biological Chemistry. 2011;286(25):22426-40. PubMed - Comments: Used in: WB |
| Murthy, Aditya; Li, Yun; Peng, Ivan; Reichelt, Mike; Katakam, Anand Kumar; Noubade, Rajkumar; Roose-Girma, Merone; DeVoss, Jason; Diehl, Lauri; Graham, Robert R; van Lookeren Campagne, Menno. A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3. Nature. 2014;506(7489):456-62. PubMed - Comments: Used in: WB |
| Morozova, Kateryna; Sridhar, Sunandini; Zolla, Valerio; Clement, Cristina C; Scharf, Brian; Verzani, Zoe; Diaz, Antonio; Larocca, Jorge N; Hajjar, Katherine A; Cuervo, Ana Maria; Santambrogio, Laura. Annexin A2 promotes phagophore assembly by enhancing Atg16L⁺ vesicle biogenesis and homotypic fusion. Nature Communications. 2015;6:5856. PubMed - Comments: Used in: FCM |
| Morozova, Kateryna; Sridhar, Sunandini; Zolla, Valerio; Clement, Cristina C; Scharf, Brian; Verzani, Zoe; Diaz, Antonio; Larocca, Jorge N; Hajjar, Katherine A; Cuervo, Ana Maria; Santambrogio, Laura. Annexin A2 promotes phagophore assembly by enhancing Atg16L⁺ vesicle biogenesis and homotypic fusion. Nature Communications. 2015;6:5856. PubMed - Comments: Used in: IF |
| Boada-Romero, Emilio; Serramito-Gómez, Inmaculada; Sacristán, María P; Boone, David L; Xavier, Ramnik J; Pimentel-Muiños, Felipe X. The T300A Crohn's disease risk polymorphism impairs function of the WD40 domain of ATG16L1. Nature Communications. 2016;7:11821. PubMed - Comments: Used in: WB |
| Diamanti, Michaela A; Gupta, Jalaj; Bennecke, Moritz; De Oliveira, Tiago; Ramakrishnan, Mallika; Braczynski, Anne K; Richter, Benjamin; Beli, Petra; Hu, Yinling; Saleh, Maya; Mittelbronn, Michel; Dikic, Ivan; Greten, Florian R. IKKα controls ATG16L1 degradation to prevent ER stress during inflammation. The Journal Of Experimental Medicine. 2017;214(2):423-437. PubMed - Comments: Used in: WB |
| Asai, Emiko; Yamamoto, Masaya; Ueda, Kazuki; Waguri, Satoshi. Spatiotemporal alterations of autophagy marker LC3 in rat skin fibroblasts during wound healing process. Fukushima Journal Of Medical Science. 2018;64(1):15-22. PubMed - Comments: Used in: IHC |
| Kucharewicz, Karolina; Dudkowska, Magdalena; Zawadzka, Anna; Ogrodnik, Mikolaj; Szczepankiewicz, Andrzej A; Czarnocki, Zbigniew; Sikora, Ewa. Simultaneous induction and blockade of autophagy by a single agent. Cell Death & Disease. 2018;9(3):353. PubMed - Comments: Used in: ICC |
| Chu, Jiaqi; Fu, Yuanyuan; Xu, Jiecheng; Zheng, Xueping; Gu, Qianqian; Luo, Xia; Dai, Qi; Zhang, Shuxian; Liu, Peiqing; Hong, Liang; Li, Min. ATG4B inhibitor FMK-9a induces autophagy independent on its enzyme inhibition. Archives Of Biochemistry And Biophysics. 2018;644:29-36. PubMed - Comments: Used in: ICC |
| Slowicka, Karolina; Serramito-Gómez, Inmaculada; Boada-Romero, Emilio; Martens, Arne; Sze, Mozes; Petta, Ioanna; Vikkula, Hanna K; De Rycke, Riet; Parthoens, Eef; Lippens, Saskia; Savvides, Savvas N; Wullaert, Andy; Vereecke, Lars; Pimentel-Muiños, Felipe X; van Loo, Geert. Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis. Nature Communications. 2019;10(1):1834. PubMed - Comments: Used in: WB |
| Shizukuishi, Sayaka; Ogawa, Michinaga; Matsunaga, Satoko; Tomokiyo, Mikado; Ikebe, Tadayoshi; Fushinobu, Shinya; Ryo, Akihide; Ohnishi, Makoto. Streptococcus pneumoniae hijacks host autophagy by deploying CbpC as a decoy for Atg14 depletion. Embo Reports. 2020;21(5):e49232. PubMed - Comments: Used in: WB |
| Serramito-Gómez, Inmaculada; Boada-Romero, Emilio; Villamuera, Raquel; Fernández-Cabrera, Álvaro; Cedillo, José Luis; Martín-Regalado, Ángela; Carding, Simon; Mayer, Uli; Powell, Penny P; Wileman, Thomas; García-Higuera, Irene; Pimentel-Muiños, Felipe X. Regulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain. Nature Communications. 2020;11(1):5919. PubMed - Comments: Used in: IP |