Polyclonal Antibody targeting Atg16L for ICC, IP, WB.
| Product Specifications | |
| Application | ICC, IP, WB |
| Reactivity | Human, Mouse, Rat, Hamster |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Recombinant human ATG16L1 TV2 (85-588 a.a.) |
| Formulation | PBS containing 50% glycerol, pH 7.2. No preservative is contained. |
| Citations for Anti-Atg16L (Human) pAb – 32 Found |
| Matsunaga, Kohichi; Morita, Eiji; Saitoh, Tatsuya; Akira, Shizuo; Ktistakis, Nicholas T; Izumi, Tetsuro; Noda, Takeshi; Yoshimori, Tamotsu. Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L. The Journal Of Cell Biology. 2010;190(4):511-21. PubMed - Comments: Used in: ICC |
| Takahashi, Yoshinori; Meyerkord, Cheryl L; Hori, Tsukasa; Runkle, Kristin; Fox, Todd E; Kester, Mark; Loughran, Thomas P; Wang, Hong-Gang. Bif-1 regulates Atg9 trafficking by mediating the fission of Golgi membranes during autophagy. Autophagy. 2011;7(1):61-73. PubMed - Comments: Used in: ICC |
| Moreau, Kevin; Ravikumar, Brinda; Puri, Claudia; Rubinsztein, David C. Arf6 promotes autophagosome formation via effects on phosphatidylinositol 4,5-bisphosphate and phospholipase D. The Journal Of Cell Biology. 2012;196(4):483-96. PubMed - Comments: Used in: ICC |
| Young, Megan M; Takahashi, Yoshinori; Khan, Osman; Park, Sungman; Hori, Tsukasa; Yun, Jong; Sharma, Arun K; Amin, Shantu; Hu, Chang-Deng; Zhang, Jianke; Kester, Mark; Wang, Hong-Gang. Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis. The Journal Of Biological Chemistry. 2012;287(15):12455-68. PubMed - Comments: Used in: ICC |
| Seto, Shintaro; Tsujimura, Kunio; Horii, Toshinobu; Koide, Yukio. Autophagy adaptor protein p62/SQSTM1 and autophagy-related gene Atg5 mediate autophagosome formation in response to Mycobacterium tuberculosis infection in dendritic cells. Plos One. 8(12):e86017. PubMed - Comments: Used in: WB |
| Murthy, Aditya; Li, Yun; Peng, Ivan; Reichelt, Mike; Katakam, Anand Kumar; Noubade, Rajkumar; Roose-Girma, Merone; DeVoss, Jason; Diehl, Lauri; Graham, Robert R; van Lookeren Campagne, Menno. A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3. Nature. 2014;506(7489):456-62. PubMed - Comments: Used in: IP |
| Murthy, Aditya; Li, Yun; Peng, Ivan; Reichelt, Mike; Katakam, Anand Kumar; Noubade, Rajkumar; Roose-Girma, Merone; DeVoss, Jason; Diehl, Lauri; Graham, Robert R; van Lookeren Campagne, Menno. A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3. Nature. 2014;506(7489):456-62. PubMed |
| Ohshima, Jun; Lee, Youngae; Sasai, Miwa; Saitoh, Tatsuya; Su Ma, Ji; Kamiyama, Naganori; Matsuura, Yoshiharu; Pann-Ghill, Suh; Hayashi, Mikako; Ebisu, Shigeyuki; Takeda, Kiyoshi; Akira, Shizuo; Yamamoto, Masahiro. Role of mouse and human autophagy proteins in IFN-γ-induced cell-autonomous responses against Toxoplasma gondii. Journal Of Immunology (Baltimore, Md. : 1950). 2014;192(7):3328-35. PubMed - Comments: Used in: WB |
| Erbil, Secil; Oral, Ozlem; Mitou, Geraldine; Kig, Cenk; Durmaz-Timucin, Emel; Guven-Maiorov, Emine; Gulacti, Ferah; Gokce, Gokcen; Dengjel, Jörn; Sezerman, Osman Ugur; Gozuacik, Devrim. RACK1 Is an Interaction Partner of ATG5 and a Novel Regulator of Autophagy. The Journal Of Biological Chemistry. 2016;291(32):16753-65. PubMed - Comments: Used in: WB |
| Sakamoto, Shuichiro; Miyara, Masatsugu; Sanoh, Seigo; Ohta, Shigeru; Kotake, Yaichiro. Mild MPP(+) exposure-induced glucose starvation enhances autophagosome synthesis and impairs its degradation. Scientific Reports. 2017;7:46668. PubMed - Comments: Used in: ICC |
| Kimura, Tomonori; Jia, Jingyue; Kumar, Suresh; Choi, Seong Won; Gu, Yuexi; Mudd, Michal; Dupont, Nicolas; Jiang, Shanya; Peters, Ryan; Farzam, Farzin; Jain, Ashish; Lidke, Keith A; Adams, Christopher M; Johansen, Terje; Deretic, Vojo. Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy. The Embo Journal. 2017;36(1):42-60. PubMed - Comments: Used in: WB |
| Fletcher, Katherine; Ulferts, Rachel; Jacquin, Elise; Veith, Talitha; Gammoh, Noor; Arasteh, Julia M; Mayer, Ulrike; Carding, Simon R; Wileman, Thomas; Beale, Rupert; Florey, Oliver. The WD40 domain of ATG16L1 is required for its non-canonical role in lipidation of LC3 at single membranes. The Embo Journal. 2018;37(4) PubMed - Comments: Used in: ICC |
| Puri, Claudia; Vicinanza, Mariella; Ashkenazi, Avraham; Gratian, Matthew J; Zhang, Qifeng; Bento, Carla F; Renna, Maurizio; Menzies, Fiona M; Rubinsztein, David C. The RAB11A-Positive Compartment Is a Primary Platform for Autophagosome Assembly Mediated by WIPI2 Recognition of PI3P-RAB11A. Developmental Cell. 2018;45(1):114-131.e8. PubMed - Comments: Used in: WB |
| Sorbara, Matthew T; Foerster, Elisabeth G; Tsalikis, Jessica; Abdel-Nour, Mena; Mangiapane, Joseph; Sirluck-Schroeder, Imogen; Tattoli, Ivan; van Dalen, Rob; Isenman, David E; Rohde, John R; Girardin, Stephen E; Philpott, Dana J. Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria. Cell Host & Microbe. 2018;23(5):644-652.e5. PubMed - Comments: Used in: WB |
| Sorbara, Matthew T; Foerster, Elisabeth G; Tsalikis, Jessica; Abdel-Nour, Mena; Mangiapane, Joseph; Sirluck-Schroeder, Imogen; Tattoli, Ivan; van Dalen, Rob; Isenman, David E; Rohde, John R; Girardin, Stephen E; Philpott, Dana J. Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria. Cell Host & Microbe. 2018;23(5):644-652.e5. PubMed - Comments: Used in: ICC |
| Takahashi, Yoshinori; He, Haiyan; Tang, Zhenyuan; Hattori, Tatsuya; Liu, Ying; Young, Megan M; Serfass, Jacob M; Chen, Longgui; Gebru, Melat; Chen, Chong; Wills, Carson A; Atkinson, Jennifer M; Chen, Han; Abraham, Thomas; Wang, Hong-Gang. An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure. Nature Communications. 2018;9(1):2855. PubMed - Comments: Used in: ICC |
| Pavel, Mariana; Renna, Maurizio; Park, So Jung; Menzies, Fiona M; Ricketts, Thomas; Füllgrabe, Jens; Ashkenazi, Avraham; Frake, Rebecca A; Lombarte, Alejandro Carnicer; Bento, Carla F; Franze, Kristian; Rubinsztein, David C. Contact inhibition controls cell survival and proliferation via YAP/TAZ-autophagy axis. Nature Communications. 2018;9(1):2961. PubMed - Comments: Used in: ICC |
| Fahmy, Ahmed M; Khabir, Marwa; Blanchet, Matthieu; Labonté, Patrick. LC3B is not recruited along with the autophagy elongation complex (ATG5-12/16L1) at HCV replication site and is dispensable for viral replication. Plos One. 13(10):e0205189. PubMed - Comments: Used in: ICC |
| Scrivo, Aurora; Codogno, Patrice; Bomont, Pascale. Gigaxonin E3 ligase governs ATG16L1 turnover to control autophagosome production. Nature Communications. 2019;10(1):780. PubMed - Comments: Used in: WB |
| Scrivo, Aurora; Codogno, Patrice; Bomont, Pascale. Gigaxonin E3 ligase governs ATG16L1 turnover to control autophagosome production. Nature Communications. 2019;10(1):780. PubMed - Comments: Used in: ICC |
| Zemirli, Naïma; Boukhalfa, Asma; Dupont, Nicolas; Botti, Joëlle; Codogno, Patrice; Morel, Etienne. The primary cilium protein folliculin is part of the autophagy signaling pathway to regulate epithelial cell size in response to fluid flow. Cell Stress. 2019;3(3):100-109. PubMed - Comments: Used in: WB |
| Zemirli, Naïma; Boukhalfa, Asma; Dupont, Nicolas; Botti, Joëlle; Codogno, Patrice; Morel, Etienne. The primary cilium protein folliculin is part of the autophagy signaling pathway to regulate epithelial cell size in response to fluid flow. Cell Stress. 2019;3(3):100-109. PubMed - Comments: Used in: IF |
| Ding, Xianming; Jiang, Xiao; Tian, Rui; Zhao, Pengwei; Li, Lin; Wang, Xinyi; Chen, She; Zhu, Yushan; Mei, Mei; Bao, Shilai; Liu, Wei; Tang, Zaiming; Sun, Qiming. RAB2 regulates the formation of autophagosome and autolysosome in mammalian cells. Autophagy. 2019;15(10):1774-1786. PubMed - Comments: Used in: WB |
| Slowicka, Karolina; Serramito-Gómez, Inmaculada; Boada-Romero, Emilio; Martens, Arne; Sze, Mozes; Petta, Ioanna; Vikkula, Hanna K; De Rycke, Riet; Parthoens, Eef; Lippens, Saskia; Savvides, Savvas N; Wullaert, Andy; Vereecke, Lars; Pimentel-Muiños, Felipe X; van Loo, Geert. Physical and functional interaction between A20 and ATG16L1-WD40 domain in the control of intestinal homeostasis. Nature Communications. 2019;10(1):1834. PubMed - Comments: Used in: Co-IP |
| Tamura, Naoki; Kageyama, Shun; Komatsu, Masaaki; Waguri, Satoshi. Hyperosmotic Stress Induces Unconventional Autophagy Independent of the Ulk1 Complex. Molecular And Cellular Biology. 2019;39(16) PubMed - Comments: Used in: IF |
| De Faveri, Francesca; Chvanov, Michael; Voronina, Svetlana; Moore, Danielle; Pollock, Liam; Haynes, Lee; Awais, Muhammad; Beckett, Alison J; Mayer, Ulrike; Sutton, Robert; Criddle, David N; Prior, Ian A; Wileman, Tom; Tepikin, Alexei V. LAP-like non-canonical autophagy and evolution of endocytic vacuoles in pancreatic acinar cells. Autophagy. 2020;16(7):1314-1331. PubMed - Comments: Used in: ICC |
| Boukhalfa, Asma; Nascimbeni, Anna Chiara; Ramel, Damien; Dupont, Nicolas; Hirsch, Emilio; Gayral, Stephanie; Laffargue, Muriel; Codogno, Patrice; Morel, Etienne. PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress. Nature Communications. 2020;11(1):294. PubMed - Comments: Used in: WB |
| Boukhalfa, Asma; Nascimbeni, Anna Chiara; Ramel, Damien; Dupont, Nicolas; Hirsch, Emilio; Gayral, Stephanie; Laffargue, Muriel; Codogno, Patrice; Morel, Etienne. PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress. Nature Communications. 2020;11(1):294. PubMed - Comments: Used in: ICC |
| Besemer, Anna S; Maus, Joanna; Ax, Mirjam D A; Stein, Anna; Vo, Stella; Freese, Christian; Nalbach, Karsten; von Hilchen, Christian; Pfalzgraf, Ines F; Koziollek-Drechsler, Ingrid; Silva, Beate; Huesmann, Heike; Boukhallouk, Fatima; Florin, Luise; Kern, Andreas; Behl, Christian; Clement, Albrecht M. Receptor-mediated endocytosis 8 (RME-8)/DNAJC13 is a novel positive modulator of autophagy and stabilizes cellular protein homeostasis. Cellular And Molecular Life Sciences : Cmls. 2021;78(2):645-660. PubMed - Comments: Used in: ICC |
| Yamamoto, Yo-Hei; Kasai, Ayano; Omori, Hiroko; Takino, Tomoe; Sugihara, Munechika; Umemoto, Tetsuo; Hamasaki, Maho; Hatta, Tomohisa; Natsume, Tohru; Morimoto, Richard I; Arai, Ritsuko; Waguri, Satoshi; Sato, Miyuki; Sato, Ken; Bar-Nun, Shoshana; Yoshimori, Tamotsu; Noda, Takeshi; Nagata, Kazuhiro. ERdj8 governs the size of autophagosomes during the formation process. The Journal Of Cell Biology. 2020;219(8) PubMed - Comments: Used in: WB |
| Metje-Sprink, Janina; Groffmann, Johannes; Neumann, Piotr; Barg-Kues, Brigitte; Ficner, Ralf; Kühnel, Karin; Schalk, Amanda M; Binotti, Beyenech. Crystal structure of the Rab33B/Atg16L1 effector complex. Scientific Reports. 2020;10(1):12956. PubMed - Comments: Used in: WB |
| Serramito-Gómez, Inmaculada; Boada-Romero, Emilio; Villamuera, Raquel; Fernández-Cabrera, Álvaro; Cedillo, José Luis; Martín-Regalado, Ángela; Carding, Simon; Mayer, Uli; Powell, Penny P; Wileman, Thomas; García-Higuera, Irene; Pimentel-Muiños, Felipe X. Regulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain. Nature Communications. 2020;11(1):5919. PubMed - Comments: Used in: IP |