Anti Achaete-Scute Homolog 1 (ASH-1/MASH-1) pAb (Rabbit, Antiserum)

Cosmo Bio LTD

Catalog No: CAC-SK-T01-003

Catalog numbers beginning with "CAC" are antibodies from our exclusive Cosmo Bio Antibody Collection. Visit the CAC Antibody homepage to browse the collection list, organized by research topic.

Application: WB, IHC, IP 
Clonality: Polyclonal 
Host: Rabbit 
Purification: Serum 
Reactivity: Human, Mouse 

Component of the RPD3C(L) histone deacetylase complex (HDAC). Responsible for the deacetylation of lysine residues on the N-terminal tails of core histones (H2A, H2B, H3 and H4). Histone deacetylation is a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. ASH1 is necessary to repress HO in daughter cells to block mating-type switching through its binding to HO promoter 5'-YTGAT-3' sites. It is also involved in pseudohyphal growth.

References:
Yoshida et al. (2001) Proprotein convertase PACE4 is down-regulated by the basic helix-loop-hekix transcription factor hash-1 and MASH-1. Biochem. J. 360, 683-689.

Citations for Anti Achaete-Scute Homolog 1 (ASH-1/MASH-1) pAb (Rabbit, Antiserum) – 4 Found

The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons.
Cell Rep. 2016 Aug 2;16(5):1431-1444. doi: 10.1016/j.celrep.2016.06.090. Epub 2016 Jul 21. 

Transcription factors COUP-TFI and COUP-TFII are required for the production of granule cells in the mouse olfactory bulb.
Development. 2015 May 1;142(9):1593-605. doi: 10.1242/dev.115279. 

Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons.
Cereb Cortex. 2019 Dec 17;29(11):4831-4849. doi: 10.1093/cercor/bhz018. 

The PROK2/PROKR2 signaling pathway is required for the migration of most olfactory bulb interneurons.
J Comp Neurol. 2019 Dec 15;527(18):2931-2947. doi: 10.1002/cne.24719. Epub 2019 Jun 13.