Anti Achaete-Scute Homolog 1 (ASH-1/MASH-1) pAb (Rabbit, Antiserum)

Cosmo Bio LTD

Catalog No: CAC-SK-T01-003

Catalog numbers beginning with "CAC" are antibodies from our exclusive Cosmo Bio Antibody Collection. Visit the CAC Antibody homepage to browse the collection list, organized by research topic.

Component of the RPD3C(L) histone deacetylase complex (HDAC). Responsible for the deacetylation of lysine residues on the N-terminal tails of core histones (H2A, H2B, H3 and H4). Histone deacetylation is a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. ASH1 is necessary to repress HO in daughter cells to block mating-type switching through its binding to HO promoter 5'-YTGAT-3' sites. It is also involved in pseudohyphal growth.

References:
Yoshida et al. (2001) Proprotein convertase PACE4 is down-regulated by the basic helix-loop-hekix transcription factor hash-1 and MASH-1. Biochem. J. 360, 683-689.

Citations for Anti Achaete-Scute Homolog 1 (ASH-1/MASH-1) pAb (Rabbit, Antiserum) – 4 Found

Zhang, Qiangqiang; Zhang, Yue; Wang, Chunyang; Xu, Zhejun; Liang, Qifei; An, Lei; Li, Jiwen; Liu, Zhidong; You, Yan; He, Miao; Mao, Ying; Chen, Bin; Xiong, Zhi-Qi; Rubenstein, John L; Yang, Zhengang. The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons. Cell Reports. 2016;16(5):1431-1444. 

Zhou, Xing; Liu, Fang; Tian, Miao; Xu, Zhejun; Liang, Qifei; Wang, Chunyang; Li, Jiwen; Liu, Zhidong; Tang, Ke; He, Miao; Yang, Zhengang. Transcription factors COUP-TFI and COUP-TFII are required for the production of granule cells in the mouse olfactory bulb. Development (Cambridge, England). 2015;142(9):1593-605. 

Guo, Teng; Liu, Guoping; Du, Heng; Wen, Yan; Wei, Song; Li, Zhenmeiyu; Tao, Guangxu; Shang, Zicong; Song, Xiaolei; Zhang, Zhuangzhi; Xu, Zhejun; You, Yan; Chen, Bin; Rubenstein, John L; Yang, Zhengang. Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cerebral Cortex (New York, N.y. : 1991). 2019;29(11):4831-4849. 

Wen, Yan; Zhang, Zhuangzhi; Li, Zhenmeiyu; Liu, Guoping; Tao, Guangxu; Song, Xiaolei; Xu, Zhejun; Shang, Zicong; Guo, Teng; Su, Zihao; Chen, Haotian; You, Yan; Li, Jiada; Yang, Zhengang. The PROK2/PROKR2 signaling pathway is required for the migration of most olfactory bulb interneurons. The Journal Of Comparative Neurology. 2019;527(18):2931-2947.