Anti-ASC (TMS1) (Human) mAb (Clone: 23-4)

MBL

Catalog No: MBL-D086-3

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Monoclonal antibody of 100 µL targeting ASC for ICC, IHC, IPP, WB.

Product Specifications

• Application: ICC, IP, WB, IHC
• Reactivity: Human
• Clonality: Monoclonal IgG1
• Host: Mouse
• Immunogen: Triton X-100 insoluble fraction of HL-60 cells were treated with retinoic acid
• Formulation: 100 μg IgG in a 100 μl volume of PBS containing 50% glycerol, pH 7.2. Contains no preservatives.

Citations for Anti-ASC (TMS1) (Human) mAb (Clone: 23-4) – 8 Found

Mayor, Annick; Martinon, Fabio; De Smedt, Thibaut; Pétrilli, Virginie; Tschopp, Jürg. A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses. Nature Immunology. 2007;8(5):497-503. 
- Comments: Used in: WB

Masumoto, J; Taniguchi, S; Ayukawa, K; Sarvotham, H; Kishino, T; Niikawa, N; Hidaka, E; Katsuyama, T; Higuchi, T; Sagara, J. ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells. The Journal Of Biological Chemistry. 1999;274(48):33835-8. 

Masumoto, J; Taniguchi, S; Nakayama, J; Shiohara, M; Hidaka, E; Katsuyama, T; Murase, S; Sagara, J. Expression of apoptosis-associated speck-like protein containing a caspase recruitment domain, a pyrin N-terminal homology domain-containing protein, in normal human tissues. The Journal Of Histochemistry And Cytochemistry : Official Journal Of The Histochemistry Society. 2001;49(10):1269-75. 
- Comments: Used in: IHC

Masumoto, J; Taniguchi, S; Nakayama, K; Ayukawa, K; Sagara, J. Murine ortholog of ASC, a CARD-containing protein, self-associates and exhibits restricted distribution in developing mouse embryos. Experimental Cell Research. 2001;262(2):128-33. 

Masumoto, J; Taniguchi, S; Sagara, J. Pyrin N-terminal homology domain- and caspase recruitment domain-dependent oligomerization of ASC. Biochemical And Biophysical Research Communications. 2001;280(3):652-5. 

Bryan, Nicole B; Dorfleutner, Andrea; Kramer, Sara J; Yun, Chawon; Rojanasakul, Yon; Stehlik, Christian. Differential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes. Journal Of Inflammation (London, England). 2010;7:23. 
- Comments: Used in: WB

Bryan, Nicole B; Dorfleutner, Andrea; Kramer, Sara J; Yun, Chawon; Rojanasakul, Yon; Stehlik, Christian. Differential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes. Journal Of Inflammation (London, England). 2010;7:23. 
- Comments: Used in: ICC

Terasawa, Katsuhiko; Sagae, Satoru; Toyota, Minoru; Tsukada, Kuniko; Ogi, Kazuhiro; Satoh, Ayumi; Mita, Hiroaki; Imai, Kohzoh; Tokino, Takashi; Kudo, Ryuichi. Epigenetic inactivation of TMS1/ASC in ovarian cancer. Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research. 2004;10(6):2000-6. 
- Comments: Used in: ICC