Anti ARPC1B pAb (ATL-HPA004832 w/enhanced validation)

Catalog No:
ATL-HPA004832-25
$401.00
Application: WB, IHC 
Clonality: Polyclonal 
Host: Rabbit 
Reactivity: Human, Mouse, Rat 
Protein Description: actin related protein 2/3 complex, subunit 1B, 41kDa
Gene Name: ARPC1B
Alternative Gene Name: ARC41, p40-ARC, p41-ARC
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000029622: 94%, ENSRNOG00000000991: 94%
Entrez Gene ID: 10095
Uniprot ID: O15143
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Cognate Antibody/Antigen for Anti ARPC1B pAb (ATL-HPA004832 w/enhanced validation)
Antigen PrEST Antigen ARPC1B (ATL-APrEST86831)
Documents & Links for Anti ARPC1B pAb (ATL-HPA004832 w/enhanced validation)
Datasheet Anti ARPC1B pAb (ATL-HPA004832 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti ARPC1B pAb (ATL-HPA004832 w/enhanced validation) at Atlas

Documents & Links for Anti ARPC1B pAb (ATL-HPA004832 w/enhanced validation)
Datasheet Anti ARPC1B pAb (ATL-HPA004832 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti ARPC1B pAb (ATL-HPA004832 w/enhanced validation)

Citations for Anti ARPC1B pAb (ATL-HPA004832 w/enhanced validation) – 8 Found
Phosphoproteomic comparison of Pik3ca and Pten signalling identifies the nucleotidase NT5C as a novel AKT substrate.
Sci Rep. 2017 Jan 6;7:39985. doi: 10.1038/srep39985.  PubMed
Loss of the Arp2/3 complex component ARPC1B causes platelet abnormalities and predisposes to inflammatory disease.
Nat Commun. 2017 Apr 3;8:14816. doi: 10.1038/ncomms14816.  PubMed
ARPC1B binds WASP to control actin polymerization and curtail tonic signaling in B cells.
JCI Insight. 2021 Dec 8;6(23):e149376. doi: 10.1172/jci.insight.149376.  PubMed
Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors.
Elife. 2021 Nov 19;10:e65910. doi: 10.7554/eLife.65910.  PubMed
ARPC1B Is Associated with Lethal Prostate Cancer and Its Inhibition Decreases Cell Invasion and Migration In Vitro.
Int J Mol Sci. 2022 Jan 27;23(3):1476. doi: 10.3390/ijms23031476.  PubMed
Cortical branched actin determines cell cycle progression.
Cell Res. 2019 Jun;29(6):432-445. doi: 10.1038/s41422-019-0160-9. Epub 2019 Apr 10.  PubMed
Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity.
J Clin Invest. 2019 Dec 2;129(12):5600-5614. doi: 10.1172/JCI129388.  PubMed
Neutrophils Require Activation to Express Functional Cell-Surface Complement Receptor Immunoglobulin.
Front Immunol. 2022 Mar 4;13:840510. doi: 10.3389/fimmu.2022.840510. eCollection 2022.  PubMed