Application: WB, ICC, IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: actin related protein 2/3 complex subunit 1A
Gene Name: ARPC1A
Alternative Gene Name: Arc40, SOP2Hs, SOP2L
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000029621: 98%, ENSRNOG00000000996: 84%
Entrez Gene ID: 10552
Uniprot ID: Q92747
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: actin related protein 2/3 complex subunit 1A
Gene Name: ARPC1A
Alternative Gene Name: Arc40, SOP2Hs, SOP2L
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000029621: 98%, ENSRNOG00000000996: 84%
Entrez Gene ID: 10552
Uniprot ID: Q92747
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti ARPC1A pAb (ATL-HPA004334 w/enhanced validation) | |
| Antigen | PrEST Antigen ARPC1A (ATL-APrEST86773) |
| Documents & Links for Anti ARPC1A pAb (ATL-HPA004334 w/enhanced validation) | |
| Datasheet | Anti ARPC1A pAb (ATL-HPA004334 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti ARPC1A pAb (ATL-HPA004334 w/enhanced validation) at Atlas |
| Documents & Links for Anti ARPC1A pAb (ATL-HPA004334 w/enhanced validation) | |
| Datasheet | Anti ARPC1A pAb (ATL-HPA004334 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti ARPC1A pAb (ATL-HPA004334 w/enhanced validation) |
| Citations for Anti ARPC1A pAb (ATL-HPA004334 w/enhanced validation) – 7 Found |
| Loss of the Arp2/3 complex component ARPC1B causes platelet abnormalities and predisposes to inflammatory disease. Nat Commun. 2017 Apr 3;8:14816. doi: 10.1038/ncomms14816. PubMed |
| MICAL2 enhances branched actin network disassembly by oxidizing Arp3B-containing Arp2/3 complexes. J Cell Biol. 2021 Aug 2;220(8):e202102043. doi: 10.1083/jcb.202102043. Epub 2021 Jun 9. PubMed |
| ARPC1B binds WASP to control actin polymerization and curtail tonic signaling in B cells. JCI Insight. 2021 Dec 8;6(23):e149376. doi: 10.1172/jci.insight.149376. PubMed |
| Cortical branched actin determines cell cycle progression. Cell Res. 2019 Jun;29(6):432-445. doi: 10.1038/s41422-019-0160-9. Epub 2019 Apr 10. PubMed |
| Enhanced Dendritic Actin Network Formation in Extended Lamellipodia Drives Proliferation in Growth-Challenged Rac1(P29S) Melanoma Cells. Dev Cell. 2019 May 6;49(3):444-460.e9. doi: 10.1016/j.devcel.2019.04.007. PubMed |
| Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity. J Clin Invest. 2019 Dec 2;129(12):5600-5614. doi: 10.1172/JCI129388. PubMed |
| Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms. Biol Open. 2020 Jul 31;9(7):bio054304. doi: 10.1242/bio.054304. PubMed |