Application: WB, IHC, IP, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed:28396409).
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed:28396409).
| Documents & Links for Anti ARNT mAb (Clone 2F11) | |
| Datasheet | Anti ARNT mAb (Clone 2F11) Datasheet |
| Vendor Page | Anti ARNT mAb (Clone 2F11) at CUSABIO |
| Documents & Links for Anti ARNT mAb (Clone 2F11) | |
| Datasheet | Anti ARNT mAb (Clone 2F11) Datasheet |
| Vendor Page | Anti ARNT mAb (Clone 2F11) |
