Application: WB, IHC, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human, Rat
Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human, Rat
Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.
| Documents & Links for Anti Adenomatous polyposis coli protein (APC) mAb (Clone 5F2) | |
| Datasheet | Anti APC mAb (Clone 5F2) Datasheet |
| Vendor Page | Anti Adenomatous polyposis coli protein (APC) mAb (Clone 5F2) at CUSABIO |
| Documents & Links for Anti Adenomatous polyposis coli protein (APC) mAb (Clone 5F2) | |
| Datasheet | Anti APC mAb (Clone 5F2) Datasheet |
| Vendor Page | Anti Adenomatous polyposis coli protein (APC) mAb (Clone 5F2) |
Recombinant Human Adenomatous polyposis coli protein(APC),partial (CSB-EP001894HU)
CusaBio
$388.00 - $2,466.00
