Application: WB, IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: aldo-keto reductase family 1, member D1
Gene Name: AKR1D1
Alternative Gene Name: SRD5B1
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000038641: 63%, ENSRNOG00000013004: 65%
Entrez Gene ID: 6718
Uniprot ID: P51857
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: aldo-keto reductase family 1, member D1
Gene Name: AKR1D1
Alternative Gene Name: SRD5B1
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000038641: 63%, ENSRNOG00000013004: 65%
Entrez Gene ID: 6718
Uniprot ID: P51857
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Cognate Antibody/Antigen for Anti AKR1D1 pAb (ATL-HPA057002 w/enhanced validation) | |
Antigen | PrEST Antigen AKR1D1 (ATL-APrEST83994) |
Documents & Links for Anti AKR1D1 pAb (ATL-HPA057002 w/enhanced validation) | |
Datasheet | Anti AKR1D1 pAb (ATL-HPA057002 w/enhanced validation) Datasheet (External Link) |
Vendor Page | Anti AKR1D1 pAb (ATL-HPA057002 w/enhanced validation) at Atlas |
Documents & Links for Anti AKR1D1 pAb (ATL-HPA057002 w/enhanced validation) | |
Datasheet | Anti AKR1D1 pAb (ATL-HPA057002 w/enhanced validation) Datasheet (External Link) |
Vendor Page | Anti AKR1D1 pAb (ATL-HPA057002 w/enhanced validation) |
Citations for Anti AKR1D1 pAb (ATL-HPA057002 w/enhanced validation) – 4 Found |
AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells. J Steroid Biochem Mol Biol. 2019 May;189:218-227. doi: 10.1016/j.jsbmb.2019.02.002. Epub 2019 Feb 12. PubMed |
AKR1D1 is a novel regulator of metabolic phenotype in human hepatocytes and is dysregulated in non-alcoholic fatty liver disease. Metabolism. 2019 Oct;99:67-80. doi: 10.1016/j.metabol.2019.153947. Epub 2019 Jul 19. PubMed |
Glucocorticoids regulate AKR1D1 activity in human liver in vitro and in vivo. J Endocrinol. 2020 May;245(2):207-218. doi: 10.1530/JOE-19-0473. PubMed |
Differential activity and expression of human 5β-reductase (AKR1D1) splice variants. J Mol Endocrinol. 2021 Mar;66(3):181-194. doi: 10.1530/JME-20-0160. PubMed |