Application: ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. Possesses RNA slicer activity but only on select RNAs bearing 5'- and 3'-flanking sequences to the region of guide-target complementarity (PubMed:29040713).
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. Possesses RNA slicer activity but only on select RNAs bearing 5'- and 3'-flanking sequences to the region of guide-target complementarity (PubMed:29040713).
| Documents & Links for Anti AGO3 mAb (Clone 4F7) | |
| Datasheet | Anti AGO3 mAb (Clone 4F7) Datasheet |
| Vendor Page | Anti AGO3 mAb (Clone 4F7) at CUSABIO |
| Documents & Links for Anti AGO3 mAb (Clone 4F7) | |
| Datasheet | Anti AGO3 mAb (Clone 4F7) Datasheet |
| Vendor Page | Anti AGO3 mAb (Clone 4F7) |
