Application: WB, ICC, IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: adenosine deaminase, RNA-specific
Gene Name: ADAR
Alternative Gene Name: ADAR1, G1P1, IFI4
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000027951: 86%, ENSRNOG00000020744: 85%
Entrez Gene ID: 103
Uniprot ID: P55265
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human
Protein Description: adenosine deaminase, RNA-specific
Gene Name: ADAR
Alternative Gene Name: ADAR1, G1P1, IFI4
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000027951: 86%, ENSRNOG00000020744: 85%
Entrez Gene ID: 103
Uniprot ID: P55265
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti ADAR pAb (ATL-HPA003890 w/enhanced validation) | |
| Antigen | PrEST Antigen ADAR (ATL-APrEST86657) |
| Documents & Links for Anti ADAR pAb (ATL-HPA003890 w/enhanced validation) | |
| Datasheet | Anti ADAR pAb (ATL-HPA003890 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti ADAR pAb (ATL-HPA003890 w/enhanced validation) at Atlas |
| Documents & Links for Anti ADAR pAb (ATL-HPA003890 w/enhanced validation) | |
| Datasheet | Anti ADAR pAb (ATL-HPA003890 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti ADAR pAb (ATL-HPA003890 w/enhanced validation) |
| Citations for Anti ADAR pAb (ATL-HPA003890 w/enhanced validation) – 10 Found |
| How asbestos drives the tissue towards tumors: YAP activation, macrophage and mesothelial precursor recruitment, RNA editing, and somatic mutations. Oncogene. 2018 May;37(20):2645-2659. doi: 10.1038/s41388-018-0153-z. Epub 2018 Mar 6. PubMed |
| Decreased A-to-I RNA editing as a source of keratinocytes' dsRNA in psoriasis. RNA. 2018 Jun;24(6):828-840. doi: 10.1261/rna.064659.117. Epub 2018 Mar 28. PubMed |
| Double-Stranded RNA Structural Elements Holding the Key to Translational Regulation in Cancer: The Case of Editing in RNA-Binding Motif Protein 8A. Cells. 2021 Dec 15;10(12):3543. doi: 10.3390/cells10123543. PubMed |
| Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature. Nat Genet. 2012 Nov;44(11):1243-8. doi: 10.1038/ng.2414. Epub 2012 Sep 23. PubMed |
| ADAR-related activation of adenosine-to-inosine RNA editing during regeneration. Stem Cells Dev. 2013 Aug 15;22(16):2254-67. doi: 10.1089/scd.2013.0104. Epub 2013 May 3. PubMed |
| MicroRNA editing facilitates immune elimination of HCMV infected cells. PLoS Pathog. 2014 Feb 27;10(2):e1003963. doi: 10.1371/journal.ppat.1003963. eCollection 2014 Feb. PubMed |
| A novel immune resistance mechanism of melanoma cells controlled by the ADAR1 enzyme. Oncotarget. 2015 Oct 6;6(30):28999-9015. doi: 10.18632/oncotarget.4905. PubMed |
| ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis. RNA Biol. 2017 May 4;14(5):587-602. doi: 10.1080/15476286.2016.1203501. Epub 2016 Jun 30. PubMed |
| Heterogeneous RNA editing and influence of ADAR2 on mesothelioma chemoresistance and the tumor microenvironment. Mol Oncol. 2022 Dec;16(22):3949-3974. doi: 10.1002/1878-0261.13322. Epub 2022 Oct 31. PubMed |
| ADAR1 downregulation by autophagy drives senescence independently of RNA editing by enhancing p16(INK4a) levels. Nat Cell Biol. 2022 Aug;24(8):1202-1210. doi: 10.1038/s41556-022-00959-z. Epub 2022 Jul 18. PubMed |