Application: WB, ICC, IHC
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse, Rat
Protein Description: acetyl-CoA acetyltransferase 1
Gene Name: ACAT1
Alternative Gene Name: ACAT, THIL
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000032047: 92%, ENSRNOG00000007862: 92%
Entrez Gene ID: 38
Uniprot ID: P24752
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse, Rat
Protein Description: acetyl-CoA acetyltransferase 1
Gene Name: ACAT1
Alternative Gene Name: ACAT, THIL
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000032047: 92%, ENSRNOG00000007862: 92%
Entrez Gene ID: 38
Uniprot ID: P24752
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
| Cognate Antibody/Antigen for Anti ACAT1 pAb (ATL-HPA004428 w/enhanced validation) | |
| Antigen | PrEST Antigen ACAT1 (ATL-APrEST86794) |
| Documents & Links for Anti ACAT1 pAb (ATL-HPA004428 w/enhanced validation) | |
| Datasheet | Anti ACAT1 pAb (ATL-HPA004428 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti ACAT1 pAb (ATL-HPA004428 w/enhanced validation) at Atlas |
| Documents & Links for Anti ACAT1 pAb (ATL-HPA004428 w/enhanced validation) | |
| Datasheet | Anti ACAT1 pAb (ATL-HPA004428 w/enhanced validation) Datasheet (External Link) |
| Vendor Page | Anti ACAT1 pAb (ATL-HPA004428 w/enhanced validation) |
| Citations for Anti ACAT1 pAb (ATL-HPA004428 w/enhanced validation) – 9 Found |
| Skeletal muscle PGC-1α modulates systemic ketone body homeostasis and ameliorates diabetic hyperketonemia in mice. FASEB J. 2016 May;30(5):1976-86. doi: 10.1096/fj.201500128. Epub 2016 Feb 5. PubMed |
| Epigenetic Inactivation of Acetyl-CoA Acetyltransferase 1 Promotes the Proliferation and Metastasis in Nasopharyngeal Carcinoma by Blocking Ketogenesis. Front Oncol. 2021 Aug 16;11:667673. doi: 10.3389/fonc.2021.667673. eCollection 2021. PubMed |
| Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. J Proteomics. 2012 Apr 3;75(7):2236-51. doi: 10.1016/j.jprot.2012.01.030. Epub 2012 Feb 15. PubMed |
| Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer prevention. Cell Cycle. 2013 Jan 15;12(2):289-301. doi: 10.4161/cc.23109. Epub 2012 Jan 15. PubMed |
| Retinal Hypercholesterolemia Triggers Cholesterol Accumulation and Esterification in Photoreceptor Cells. J Biol Chem. 2016 Sep 23;291(39):20427-39. doi: 10.1074/jbc.M116.744656. Epub 2016 Aug 11. PubMed |
| Muscle PGC-1α is required for long-term systemic and local adaptations to a ketogenic diet in mice. Am J Physiol Endocrinol Metab. 2017 May 1;312(5):E437-E446. doi: 10.1152/ajpendo.00361.2016. Epub 2017 Feb 21. PubMed |
| Inactivation of 3-hydroxybutyrate dehydrogenase type 2 promotes proliferation and metastasis of nasopharyngeal carcinoma by iron retention. Br J Cancer. 2020 Jan;122(1):102-110. doi: 10.1038/s41416-019-0638-8. Epub 2019 Dec 10. PubMed |
| Dysregulation of Ketone Body Metabolism Is Associated With Poor Prognosis for Clear Cell Renal Cell Carcinoma Patients. Front Oncol. 2019 Dec 17;9:1422. doi: 10.3389/fonc.2019.01422. eCollection 2019. PubMed |
| Prostate cancer castrate resistant progression usage of non-canonical androgen receptor signaling and ketone body fuel. Oncogene. 2021 Nov;40(44):6284-6298. doi: 10.1038/s41388-021-02008-9. Epub 2021 Sep 28. PubMed |