Anti-1-methyladenosine (m1A) mAb (Clone: AMA-2)

Catalog No:
MBL-D345-3

Availability: 12PM PT on Dec. 3, 2024

Monoclonal antibody of 100 µl targeting 1-methyladenosine m1A for IPP, ICC, IHC, ELISA.

Product Specifications
Application ICC, IP, IHC, ELISA
Clonality Monoclonal IgG2b ĸ
Host Mouse
Immunogen KLH-conjugated 1-methyladenosine (KLH-m1A)
Formulation 1 mg/mL in PBS/50% glycerol, pH 7.2

Citations for Anti-1-methyladenosine (m1A) mAb (Clone: AMA-2) – 15 Found
Mishima, Eikan; Jinno, Daisuke; Akiyama, Yasutoshi; Itoh, Kunihiko; Nankumo, Shinnosuke; Shima, Hisato; Kikuchi, Koichi; Takeuchi, Yoichi; Elkordy, Alaa; Suzuki, Takehiro; Niizuma, Kuniyasu; Ito, Sadayoshi; Tomioka, Yoshihisa; Abe, Takaaki. Immuno-Northern Blotting: Detection of RNA Modifications by Using Antibodies against Modified Nucleosides. Plos One. 10(11):e0143756.  PubMed
Dominissini, Dan; Nachtergaele, Sigrid; Moshitch-Moshkovitz, Sharon; Peer, Eyal; Kol, Nitzan; Ben-Haim, Moshe Shay; Dai, Qing; Di Segni, Ayelet; Salmon-Divon, Mali; Clark, Wesley C; Zheng, Guanqun; Pan, Tao; Solomon, Oz; Eyal, Eran; Hershkovitz, Vera; Han, Dali; Doré, Louis C; Amariglio, Ninette; Rechavi, Gideon; He, Chuan. The dynamic N(1)-methyladenosine methylome in eukaryotic messenger RNA. Nature. 2016;530(7591):441-6.  PubMed
Comments: Used in: IP
Dominissini, Dan; Nachtergaele, Sigrid; Moshitch-Moshkovitz, Sharon; Peer, Eyal; Kol, Nitzan; Ben-Haim, Moshe Shay; Dai, Qing; Di Segni, Ayelet; Salmon-Divon, Mali; Clark, Wesley C; Zheng, Guanqun; Pan, Tao; Solomon, Oz; Eyal, Eran; Hershkovitz, Vera; Han, Dali; Doré, Louis C; Amariglio, Ninette; Rechavi, Gideon; He, Chuan. The dynamic N(1)-methyladenosine methylome in eukaryotic messenger RNA. Nature. 2016;530(7591):441-6.  PubMed
Comments: Used in: DB
Li, Xiaoyu; Xiong, Xushen; Wang, Kun; Wang, Lixia; Shu, Xiaoting; Ma, Shiqing; Yi, Chengqi. Transcriptome-wide mapping reveals reversible and dynamic N(1)-methyladenosine methylome. Nature Chemical Biology. 2016;12(5):311-6.  PubMed
Comments: Used in: IP
Li, Xiaoyu; Xiong, Xushen; Wang, Kun; Wang, Lixia; Shu, Xiaoting; Ma, Shiqing; Yi, Chengqi. Transcriptome-wide mapping reveals reversible and dynamic N(1)-methyladenosine methylome. Nature Chemical Biology. 2016;12(5):311-6.  PubMed
Comments: Used in: DB
Waku, Tsuyoshi; Nakajima, Yuka; Yokoyama, Wataru; Nomura, Naoto; Kako, Koichiro; Kobayashi, Akira; Shimizu, Toshiyuki; Fukamizu, Akiyoshi. NML-mediated rRNA base methylation links ribosomal subunit formation to cell proliferation in a p53-dependent manner. Journal Of Cell Science. 2016;129(12):2382-93.  PubMed
Comments: Used in: IP
Liu, Fange; Clark, Wesley; Luo, Guanzheng; Wang, Xiaoyun; Fu, Ye; Wei, Jiangbo; Wang, Xiao; Hao, Ziyang; Dai, Qing; Zheng, Guanqun; Ma, Honghui; Han, Dali; Evans, Molly; Klungland, Arne; Pan, Tao; He, Chuan. ALKBH1-Mediated tRNA Demethylation Regulates Translation. Cell. 2016;167(3):816-828.e16.  PubMed
Comments: Used in: DB
Ueda, Yuko; Ooshio, Ikumi; Fusamae, Yasuyuki; Kitae, Kaori; Kawaguchi, Megumi; Jingushi, Kentaro; Hase, Hiroaki; Harada, Kazuo; Hirata, Kazumasa; Tsujikawa, Kazutake. AlkB homolog 3-mediated tRNA demethylation promotes protein synthesis in cancer cells. Scientific Reports. 2017;7:42271.  PubMed
Comments: Used in: ICC
Ueda, Yuko; Ooshio, Ikumi; Fusamae, Yasuyuki; Kitae, Kaori; Kawaguchi, Megumi; Jingushi, Kentaro; Hase, Hiroaki; Harada, Kazuo; Hirata, Kazumasa; Tsujikawa, Kazutake. AlkB homolog 3-mediated tRNA demethylation promotes protein synthesis in cancer cells. Scientific Reports. 2017;7:42271.  PubMed
Comments: Used in: DB
Safra, Modi; Sas-Chen, Aldema; Nir, Ronit; Winkler, Roni; Nachshon, Aharon; Bar-Yaacov, Dan; Erlacher, Matthias; Rossmanith, Walter; Stern-Ginossar, Noam; Schwartz, Schraga. The m1A landscape on cytosolic and mitochondrial mRNA at single-base resolution. Nature. 2017;551(7679):251-255.  PubMed
Comments: Used in: IP
Li, Xiaoyu; Xiong, Xushen; Zhang, Meiling; Wang, Kun; Chen, Ying; Zhou, Jun; Mao, Yuanhui; Lv, Jia; Yi, Danyang; Chen, Xiao-Wei; Wang, Chu; Qian, Shu-Bing; Yi, Chengqi. Base-Resolution Mapping Reveals Distinct m(1)A Methylome in Nuclear- and Mitochondrial-Encoded Transcripts. Molecular Cell. 2017;68(5):993-1005.e9.  PubMed
Comments: Used in: IP
Elkordy, Alaa; Mishima, Eikan; Niizuma, Kuniyasu; Akiyama, Yasutoshi; Fujimura, Miki; Tominaga, Teiji; Abe, Takaaki. Stress-induced tRNA cleavage and tiRNA generation in rat neuronal PC12 cells. Journal Of Neurochemistry. 2018;146(5):560-569.  PubMed
Mishima, Eikan; Abe, Takaaki. Immuno-Northern Blotting: Detection of Modified RNA Using Gel Separation and Antibodies to Modified Nucleosides. Methods In Molecular Biology (Clifton, N.j.). 1870:179-187.  PubMed
Elkordy, Alaa; Rashad, Sherif; Shehabeldeen, Heba; Mishima, Eikan; Niizuma, Kuniyasu; Abe, Takaaki; Tominaga, Teiji. tiRNAs as a novel biomarker for cell damage assessment in in vitro ischemia-reperfusion model in rat neuronal PC12 cells. Brain Research. 2019;1714:8-17.  PubMed
Comments: Used in: NB
Sato, Kanako; Rashad, Sherif; Niizuma, Kuniyasu; Tominaga, Teiji. Stress Induced tRNA Halves (tiRNAs) as Biomarkers for Stroke and Stroke Therapy; Pre-clinical Study. Neuroscience. 2020;434:44-54.  PubMed