Alpha-Synuclein, Recombinant, Mouse

Cosmo Bio LTD

Catalog No: CSR-SYN06-1

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E. coli expressed mouse α-synuclein has been widely used in structural and functional studies. Masuda et. al. (1)  have reported that approximately 20% of E. coli expressed mouse α-syn is mistranslated resulting in a Cys residue instead of Tyr at position 136 and causing an increase in the levels of dimeric α-synuclein.

CSR-SYN04 is E. coli human alpha-Synuclein (human) expressed from a plasmid in which the TAC codon coding for Tyr136 in the mouse protein is replaced by TAT to produce protein expressing Tyr at position 136 homogenously. It can be used as mouse α-syn under similar conditions to that of in vivo.

This product can also be used for comparison (control) of mouse α-Synuclein Fibrils (CSR-SYN05).

Source: Mouse
Expression system: E. coli
Concentration: 1mg/mL
Purity: ≥ 90% (SDS-Page)
Storage: -20°C

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Alpha-Synuclein, Recombinant, Mouse	CSR-SYN06