About Cosmo Bio USA Suppliers:
UBIQUIGENT

	Expert Reagents and Services for Ubiquitin-Proteasome Pathway Research and Drug Discovery
	Antibodies Cell Lines Deubiquitylating Enzymes (DUBS) DUB Substrates E1 Activating Enzymes E2 Conjugating Enzymes E3 Ligases  Kinsases	Substrates  Kits Lysates  Phospho Ubiquitins Proteasome  Ubiquitin Binding Proteins Ubiquitin Chains Ubiquitin/Ubl Modifiers
	Supplier Name: Ubiquigent Ltd. Supplier Location: Dundee, Scotland, UK Founding Date: 2009 Distributed by Cosmo Bio USA Since: 2012 Supplier Website: http://www.ubiquigent.com CBU Supplier Code (cat. no. prefix): UBI-

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About Ubiquigent

Ubiquigent Limited is a specialist developer and supplier of Drug Discovery Services, high quality Research Tools and Chemistry to the life science research community worldwide.

Ubiquigent’s scientific and business interests have a clear focus; namely the ubiquitin, ubiquitin-like, and integrated signalling systems.

The Company has established its scientific and business credentials with both academic researchers undertaking fundamental scientific discovery and pharmaceutical and biotechnology company scientists exploring the potential of ubiquitin cascade-focused drug discovery.

Ubiquigent benefits from high calibre backing including from private US investors, the UK Medical Research Council, and the University of Dundee. The Company’s headquarters and laboratory operations are based in the UK and are located in a state-of-the-art facility adjacent to the MRC Protein Phosphorylation and Ubiquitylation Unit at the University of Dundee (both founded by Professor Sir Philip Cohen). In addition to Ubiquigent’s own facilities and capabilities, such proximity provides ready access to a huge range of additional scientific expertise (1,000+ life-science researchers on site), technological competencies, and assay and analytical platforms.

Ubiquigent staff have a wealth of scientific experience, technological competencies and commercial expertise, gained from within academia, the life science research reagents and services sector, and the pharmaceutical industry, that enables the Company to offer a level of understanding and service to its customers and clients worldwide that few companies may match.

 

Ubiquigent Product Index

 Antibodies from Ubiquigent

ABIN1 (human; full length), pAb
ABIN1 (mouse; full length), pAb
AMPK alpha 2 (human; residues 352 – 366), pAb
CAND1 (human; residues 5 – 245), pAb
Cullin3 (human; residues 554 - 768), pAb
Cullin5 (human; residues 577 – 689), pAb
CYLD (human; full length), pAb
DCNL3 (human; full length), pAb
DCNL4 (human; full length), pAb
DCNL5 (human; full length), pAb
DCNL5 (mouse; full length), pAb
FAF1 (human; full length), pAb
FOXO3A pSer294 (human; residues 289 - 298), pAb
FOXO3A pSer344 (mouse; residues 339 - 348), pAb
FOXO3A pSer7 (mouse; residues 3 - 11), pAb
HOIL1 (human; full length), pAb
HOIP (human; full length), pAb
IKK beta (human; full length), pAb
IKK epsilon (human; residues 701-716), pAb
IKK epsilon (mouse; residues 702-717), pAb
IKK epsilon pSer172 (human; residues 168–177), pAb
MAPK15 (human; full length), pAb
Mono and Polyubiquitylated conjugates, mAb (FK2)
Mono and Polyubiquitylated conjugates, mAb (FK2) Biotin linked
Mono and Polyubiquitylated conjugates, mAb (FK2) HRP linked
MYPT1 (human; residues 728 – 838), pAb
MYPT1 pSer445 (mouse; residues 437 - 452), pAb
MYPT1 pSer472 (mouse; residues 466-478), pAb
MYPT1 pSer554 (mouse; residues 547-618), pAb
MYPT1 pSer909 (mouse; residues 903-917), pAb
MYPT1 pThr34 (mouse; residues 27 - 41), pAb
MYPT2 (human; residues 350-450), pAb
MYPT3 (human; full length), pAb
NEMO (human; full length), pAb
Optineurin (human; full length), pAb
OTUB1 (human; full length), pAb
OTULIN (human; full length), pAb
Parkin (human; full length), pAb
Parkin pSer65 (human; residues 60 - 72), pAb
PINK1 (human; residues 175 – 250), pAb
PINK1 pThr257 (human; residues 250 - 262), pAb
PKB alpha (human; residues 1-147), pAb
PKB beta (mouse; residues 455-469), pAb
PKB gamma (human; residues 116-127), pAb
Polyubiquitylated conjugates, mAb (FK1)
RNF7 (human; full length), pAb
SGK1 (human; full length), pAb
SGK1 (human; residues 412 – 431), pAb
SGK2 (human; residues 333 – 346), pAb
SGK3 (human; full length), pAb
SHARPIN (human; full length), pAb
TBK1 (human; full length), pAb
TBK1 pSer172 (human; residues 168 – 177), pAb
TRAF6 (mouse; full length), pAb
TRIAD1 (human; full length), pAb
TRIM65 (human; full length), pAb
UBE2M (mouse; full length), pAb
UBE2T (human; full length), pAb
UBXD7 (human; full length), pAb
USP11 (human; full length), pAb
USP15 (human; full length), pAb

Cell Lines from Ubiquigent (all discontinued)

Proteaselect-HEK293_Bio-Rpn11
Ubiselect Kit
Ubiselect-MEF_Bio-Ub(P0)
Ubiselect-MEF_BirA(P0)

Deubiquitylating Enzymes (DUBS) from Ubiquigent

A20 CD(1-366) [GST-tagged]
AMSH CD(252-424) [GST-tagged]
AMSH-LP CD(264-436) [GST-tagged]
Ataxin-3 [GST-tagged]
Ataxin-3L [6His-tagged]
BAP1 [GST-tagged]
CYLD [6His-tagged]
JOSD1 [6His-tagged]
JOSD2 [6His-tagged]
OTU1 [GST-tagged]
OTUB1 [GST-tagged]
OTUB2 [GST-tagged]
OTUD1 CD(270-481) [6His-tagged]
OTUD3 [GST-tagged]
OTUD5(p177S) [GST-tagged]
OTUD6A [6His-tagged]
OTUD6B [GST-tagged]
OTULIN [GST-tagged]
TRABID CD(245-697) [6His-tagged]
UCHL1 [6His-tagged]
UCHL3 [GST-tagged]
UCHL5 [GST-tagged]
USP1 [6His-tagged]/UAF1 [untagged]
USP14 & 26S Proteasome [Ub-VS treated]
USP14 [6His-tagged]
USP15 (isoform 2) [untagged]
USP19 -TM(1-1290) [GST-tagged]
USP2 (isoform 4) [GST-tagged]
USP20 [GST-tagged]
USP21 CD(196-565) [GST-tagged]
USP25 [GST-tagged]
USP27X [DAC-tagged]
USP28 [GST-tagged]
USP30 CD(57-517) [untagged]
USP36 CD(81-461) [GST-tagged]
USP4 [6His-tagged]
USP5 [6His-tagged]
USP6 CD(529-1406) [GST-tagged]
USP7 [6His-tagged]
USP8 [untagged]
USP9x CD(1554-1995) [GST-tagged]
VCPIP CD(25-561) [GST-tagged]

DUB Substrates from Ubiquigent

Ubiquitin-AMC
Ubiquitin-Lys-TAMRA (5-TAMRA-Lys(Ub)-Gly-OH)
Ubiquitin-Rhodamine 110

 

E1 Activating Enzymes from Ubiquigent

APP-BP1 [untagged] / UBA3 [untagged]
ATG7 [6His-tagged]
SAE1 [GST-tagged] / SAE2 [6His-tagged]
UBA6 [6His-tagged]
UBA7 [6His-tagged]
UBE1 [6His-tagged]

 

E2 Conjugating Enzymes from Ubiquigent

UBE2A (HR6A) [6His-tagged]
UBE2A (HR6A) [GST-tagged]
UBE2A (HR6A) [untagged]
UBE2B (HR6B) [6His-tagged]
UBE2B (HR6B) [GST-tagged]
UBE2B (HR6B) [untagged]
UBE2C (UbcH10) [6His-tagged]
UBE2C (UbcH10) [GST-tagged]
UBE2C (UbcH10) [untagged]
UBE2D1 (UbcH5a) [6His-tagged]
UBE2D1 (UbcH5a) [GST-tagged]
UBE2D1 (UbcH5a) [untagged]
UBE2D2 (UbcH5b) [6His-tagged]
UBE2D2 (UbcH5b) [GST-tagged]
UBE2D2 (UbcH5b) [untagged]
UBE2D3 (UbcH5c) [6His-tagged]
UBE2D3 (UbcH5c) [GST-tagged]
UBE2D3 (UbcH5c) [untagged]
UBE2D4 (UbcH5d) [6His-tagged]
UBE2D4 (UbcH5d) [GST-tagged]
UBE2D4 (UbcH5d) [untagged]
UBE2E1 (UbcH6) [6His-tagged]
UBE2E1 (UbcH6) [GST-tagged]
UBE2E1 (UbcH6) [untagged]
UBE2E2 (UbcH8) [6His-tagged]
UBE2E2 (UbcH8) [GST-tagged]
UBE2E2 (UbcH8) [untagged]
UBE2E3 (UbcH9) [6His-tagged]
UBE2E3 (UbcH9) [GST-tagged]
UBE2E3 (UbcH9) [untagged]
UBE2F (NCE2) [6His-tagged]
UBE2F (NCE2) [GST-tagged]
UBE2F (NCE2) [untagged]
UBE2G1(Ubc7) [6His-tagged]
UBE2G1(Ubc7) [GST-tagged]
UBE2G1(Ubc7) [untagged]
UBE2G2 (Ubc7) [6His-tagged]
UBE2G2 (Ubc7) [GST-tagged]
UBE2G2 (Ubc7) [untagged]
UBE2H (UbcH2) [6His-tagged]
UBE2H (UbcH2) [GST-tagged]
UBE2H (UbcH2) [untagged]
UBE2I (Ubc9) [6His-tagged]
UBE2I (Ubc9) [GST-tagged]
UBE2I (Ubc9) [untagged]
UBE2J1 (NCUBE1) residues (1-282) [6His-tagged]
UBE2J2 (NCUBE2) residues (1-226) [6His-tagged]
UBE2J2 (NCUBE2) residues (1-226) [GST-tagged]
UBE2J2 (NCUBE2) residues (1-226) [untagged]
UBE2K (UbcH1) [6His-tagged]
UBE2K (UbcH1) [GST-tagged]
UBE2K (UbcH1) [untagged]
UBE2L3 (UbcH7) [6His-tagged]
UBE2L3 (UbcH7) [GST-tagged]
UBE2L3 (UbcH7) [untagged]
UBE2L6 (UbcH8) [6His-tagged]
UBE2L6 (UbcH8) [GST-tagged]
UBE2L6 (UbcH8) [untagged]
UBE2M (Ubc12) [6His-tagged]
UBE2M (Ubc12) [GST-tagged]
UBE2M (Ubc12) [untagged]
UBE2N (UBC13) [6His-tagged]
UBE2N (UBC13) [GST-tagged]
UBE2N (UBC13) [untagged]
UBE2Q1 (NICE-5) [6His-tagged]
UBE2Q1 (NICE-5) [GST-tagged]
UBE2Q2 [6His-tagged]
UBE2Q2 [GST-tagged]
UBE2Q2 [untagged]
UBE2R1 (UbcH3) [6His-tagged]
UBE2R1 (UbcH3) [GST-tagged]
UBE2R1 (UbcH3) [untagged]
UBE2R2 (CDC34B) [6His-tagged]
UBE2R2 (CDC34B) [untagged]
UBE2S (E2-EPF) [6His-tagged]
UBE2S (E2-EPF) [GST-tagged]
UBE2S (E2-EPF) [untagged]
UBE2T (HSPC150) [6His-tagged]
UBE2T (HSPC150) [GST-tagged]
UBE2T (HSPC150) [untagged]
UBE2V1 (Uev1) [6His-tagged]
UBE2V1 (Uev1) [GST-tagged]
UBE2V1 (Uev1) [untagged]
UBE2V2 (Mms2) [6His-tagged]
UBE2V2 (Mms2) [GST-tagged]
UBE2V2 (Mms2) [untagged]
UBE2W (Ubc16) [6His-tagged]
UBE2W (Ubc16) [GST-tagged]
UBE2Z (USE1) [6His-tagged]
UBE2Z (USE1) [GST-tagged]
 

E3Ligases from Ubiquigent

BIRC2 [GST-tagged]
CBL [GST-tagged]
CHIP [6His-tagged]
CHIP [GST-tagged]
CHIP [untagged]
Cul1/Rbx1 [untagged]
Cul1/Rbx1/Skp1 [untagged]
Cul2/Rbx1 [untagged]
Cul3/Rbx1 [untagged]
Cul5/Rnf7 [untagged]
DCNL1 [6His-tagged]
DCNL1 [GST-tagged]
DCNL2 [6His-tagged]
DCNL2 [GST-tagged]
HUWE1 [GST-tagged]
IDOL [6His-tagged]
IPAH9.8 [GST-tagged]
ITCH [GST-tagged]
MuRF1 [untagged]
NLEL [GST-tagged]
Parkin [untagged]
RNF11 [6His-tagged]
RNF11 [GST-tagged]
RNF8 [GST-tagged]
SMURF1 [GST-tagged]
SMURF2 [GST-tagged]
TRIAD1 [6His-tagged]
WWP1 [GST-tagged]
WWP1 [untagged]
ZNRF1 [GST-tagged]
ZNRF2 [GST-tagged]

Kinsases from Ubiquigent
AMPK alpha 1 (T172D) [GST-tagged]
AMPKA1/AMPKB2/AMPKG1 [6His-tagged]
AMPKA2/AMPKB2/AMPKG1 [6His-tagged]
B-Raf (V600E) [GST-tagged]
B-Raf [GST-tagged]
BRSK2 residues (2-674) [6His-tagged]
CHK2 [GST-tagged]
C-Raf [GST-tagged]
IKK epsilon [GST-tagged]
MAPK10 [GST-tagged]
MAPK11 [GST-tagged]
MAPK12 [GST-tagged]
MAPK14 (T106M) [GST-tagged]
MAPK14 [GST-tagged]
MAPK15 [6His-tagged]
MAPK3 [untagged]
MAPK7 [6His-tagged]
MAPK8 [6His-tagged]
MAPK9 [6His-tagged]
MARK 3 [6His-tagged]
MARK 4 [6His-tagged]
p70 S6 kinase (T412E) [6His-tagged]
PINK1 (D359A) [MBP-tagged]
PINK1 [MBP-tagged]
PKA [GST-tagged]
PKB alpha (S473D) [6His-tagged]
SGK1 (S422D) [6His-tagged]
TAK1_TAB1 complex [6His-tagged]
TBK1 [GST-tagged]

 

Substrates from Ubiquigent

PKB alpha [GST-tagged]
SGK3 [GST-tagged]

Kits from Ubiquigent
4x Ubiquitin-Rhodamine 110
5x DUB Assay Buffer discontinued
5x DUB Assay Stop Buffer discontinued
Activated USP14 DUB assay Kit
DUB Scan Kit
E2 Scan Kit version 2
USP14 Activation Kit

Lysates from Ubiquigent

HEK293 cell lysate
HEK293 cell lysate (IL-1 stimulated)

Phospho Ubiquitins from Ubiquigent

Biotin-Ahx-ubiquitin (pSer57)
Biotin-Ahx-ubiquitin (pSer65)
Biotin-Ahx-ubiquitin (pThr12)
Biotin-Ahx-ubiquitin (pThr7)
Biotin-Ahx-ubiquitin (pTyr59)
Biotin-Ahx-ubiquitin (synthetic)
Ubiquitin (pSer57)
Ubiquitin (pSer65)
Ubiquitin (synthetic)

Proteasome from Ubiquigent

26S Proteasome
26S Proteasome [Ub-VS treated]

Substrates from Ubiquigent

beta Catenin [GST-tagged]
FOXO3 [GST-tagged]
HSP27 [GST-tagged]
MYPT1 [GST-tagged]
MYPT3 [GST-tagged]

Ubiquitin Binding Proteins from Ubiquigent

NEMO (D311N) [GST-tagged]
NEMO [GST-tagged]
Optineurin (D474N) [GST-tagged]
Optineurin [GST-tagged]
S5a [GST-tagged]
S5a [untagged]
TOLLIP [GST-tagged]
TOM1 [GST-tagged]

Ubiquitin Chains  from Ubiquigent

Di-ubiquitin (K11-linked) [untagged]
Di-ubiquitin (K27-linked) [untagged]
Di-ubiquitin (K29-linked) [untagged]
Di-ubiquitin (K33-linked) [untagged]
Di-ubiquitin (K48-linked) [untagged]
Di-ubiquitin (K63-linked) [untagged]
Di-ubiquitin (K6-linked) [untagged]
Di-ubiquitin (linear) [GST-cleaved]
Poly-ubiquitin (Ub n2-7; K63-linked) [untagged]

Ubiquitin/Ubl Modifiesrs  from Ubiquigent

Biotinylated Ubiquitin
ISG15 [untagged]
LC3b [6His-tagged]
LC3b [GST-tagged]
LC3b [untagged]
NEDD8 [untagged]
SUMO1 [6His-tagged]
SUMO1 [untagged]
SUMO2 [6His-tagged]
SUMO2 [untagged]
Ubiquitin [untagged]